Noelle R. Leonard, Ph.D.
Senior Research Scientist, New York University College of Nursing
Nationally up to 60 % of persons living with HIV are neither taking antiretroviral therapy (ART) nor well engaged in HIV care, mainly racial/ethnic minorities. This study examined a new culturally targeted multi-component intervention to address emotional, attitudinal, and social/structural barriers to ART initiation and HIV care. Participants (N = 95) were African American/Black and Latino adults with CD4\500 cells/mm3 not taking ART, randomized 1:1 to intervention or control arms, the latter receiving treatment as usual. Primary endpoints were adherence, evaluated via ART concentrations in hair samples, and HIV viral load suppression. The intervention was feasible and acceptable. Eight months post-baseline, intervention participants tended to be more likely to evidence ‘‘good’’ (that is, 7 days/week) adherence (60 vs. 26.7 %; p = 0.087; OR = 3.95), and had lower viral load levels than controls (t(22) = 2.29, p = 0.032; OR = 5.20), both large effect sizes. This highly promising intervention merits further study.
Behavioral Intervention Improves Treatment Outcomes Among HIV-Infected Individuals Who Have Delayed, Declined, or Discontinued Antiretroviral Therapy: A Randomized Controlled Trial of a Novel Intervention
Marya Gwadz1 • Charles M. Cleland1 • Elizabeth Applegate1 • Mindy Belkin1 • Monica Gandhi2 • Nadim Salomon3 • Angela Banfield1 • Noelle Leonard1 • Marion Riedel4 • Hannah Wolfe5 • Isaiah Pickens1 • Kelly Bolger1 • DeShannon Bowens1 • David Perlman6 • Donna Mildvan6 • The Heart to Heart
Collaborative Research Team
At Socialgradient.org, we believe in the transformative power of science, information, and knowledge. In our weekly podcast, we discuss news and events that shed light on the disparities – in health, science, and education – that fuel and perpetuate a gradient in health and knowledge that runs along the socioeconomic spectrum. Our goal is to create science and health media accessible to everyone. We invite you to: Get news. Share information. And inspire change.
Visit our website http://www.socialgradient.org
Luis Quevedo is our host, he tweets @Luis_Quevedo
Our content and the music in this episode are distributed under a Creative Commons license.
Music by Yatch from the freemusicarchive.org
Read more at http://socialgradient.libsyn.org/#tPVzTF1HfhgqflGG.99